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Assay Detail

CHEMBL5159798

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against influenza A virus (A/Puerto Rico/8/34) H1N1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus
Cell Type MDCK
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza A virus (CHEMBL613740)
Type ORGANISM
Organism Influenza A virus

Publication

Discovery of Aryl Benzoyl Hydrazide Derivatives as Novel Potent Broad-Spectrum Inhibitors of Influenza A Virus RNA-Dependent RNA Polymerase (RdRp).
Liu X, Liang J, Yu Y, Han X, Yu L, Chen F, Xu Z, Chen Q, Jin M, Dong C, Zhou HB, Lan K, Wu S.
J Med Chem (2022) 65 : 3814 -3832
PubMed 35212527 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3318007 PIMODIVIR 3.0 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3318007 PIMODIVIR EC50 = 0.3 nM 9.52