Assay Detail
Binding
CHEMBL5162254
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of STING mediated immune response in human THP-1 cells assessed as induction of IFNbeta secretion measured after 24 hrs by ELISA
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | THP-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Stimulator of interferon genes protein (CHEMBL4523377) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.70 | 8.70 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201766 | — | — | 2 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201766 | — | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL5201766 | — | Activity | - | — | - |