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Assay Detail

CHEMBL5165397

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Functional
Antiproliferative activity against human SNU-475 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SNU-475
Confidence 1 — Organism
Curated By Autocuration

Target

SNU-475 (CHEMBL1075586)
Type CELL-LINE
Organism Homo sapiens

Publication

Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer.
Kuang Y, Ye N, Kyani A, Ljungman M, Paulsen M, Chen H, Zhou M, Wild C, Chen H, Zhou J, Neamati N.
J Med Chem (2022) 65 : 6133 -6156
PubMed 35439009 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2097911 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2097911 IC50 = 2670.0 nM 5.57