Assay Detail
Binding
CHEMBL5167466
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human recombinant LC3B assessed as dissociation constant incubated for 30 mins by fluorescence anisotropy assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Microtubule-associated proteins 1A/1B light chain 3B (CHEMBL4879514) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Ispinesib as an Effective Warhead for the Design of Autophagosome-Tethering Chimeras: Discovery of Potent Degraders of Nicotinamide Phosphoribosyltransferase (NAMPT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.76 | 6.76 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180355 | — | — | 1 | 6.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180355 | — | Kd | = | 175.0 | nM | 6.76 |