Assay Detail
Functional
CHEMBL5209612
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Substrate uptake by the Peptide Transporter 2 (PEPT2, SLC15A2) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC15A2 cells (PubChem AID: 1794819)
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Solute carrier family 15 member 2 (CHEMBL1743125) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Membrane potential based assay for SLC15A2 using HEK-293 SLC15A2 OE cells
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.48 | 4.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL242948 | CARNOSINE | 3.0 | 1 | 4.55 |
| CHEMBL175737 | GLYCYLSARCOSINE | — | 2 | 4.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL242948 | CARNOSINE | EC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL175737 | GLYCYLSARCOSINE | EC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL175737 | GLYCYLSARCOSINE | EC50 | = | 123000.0 | nM | - |