Assay Detail
Binding
CHEMBL5209682
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Cellular target engagement assay with: MAPK9
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Category | NanoBRET assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
NanoBRET assay results for EUbOPEN Chemogenomics Library 3
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.55 | 6.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1950289 | TANZISERTIB | 2.0 | 1 | 6.83 |
| CHEMBL4082278 | — | — | 1 | 6.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1950289 | TANZISERTIB | IC50 | = | 147.9 | nM | 6.83 |
| CHEMBL4082278 | — | IC50 | = | 531.7 | nM | 6.27 |