Assay Detail
Functional
CHEMBL5210010
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Affinity Phenotypic Cellular interaction (TNF-a release (stimmulated by LPS in human WB)) EUB0000718a MAPK11
1
Total Activities
1
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Category | Affinity phenotypic cellular assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Affinity Phenotypic Cellular Literature for EUbOPEN Chemogenomics Library wave 3
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.42 | 7.42 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Mode of action | Mode of action | - | — | Inhibitor |
| Negative control | Negative control | - | — | FM-743 |
| Protein family | Protein family | - | — | Protein Kinase |
| Recommended concentration | Recommended concentration | 1.0 | uM | — |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2316207 | FS-694 | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2316207 | FS-694 | IC50 | = | 38.0 | nM | 7.42 |