Assay Detail
Binding
CHEMBL5210381
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Affinity Biochemical interaction (Radiometric kinase assay) EUB0000677a PLK1
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Category | Affinity biochemical assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase PLK1 (CHEMBL3024) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Affinity Biochemical Literature for EUbOPEN Chemogenomics Library wave 3
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.70 | 8.70 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Mode of action | Mode of action | - | — | Inhibitor |
| Protein family | Protein family | - | — | Protein Kinase |
| Recommended concentration | Recommended concentration | 100.0 | nM | — |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1738758 | ONVANSERTIB | 2.0 | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1738758 | ONVANSERTIB | IC50 | = | 2.0 | nM | 8.70 |