Assay Detail

CHEMBL5213670

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Binding

Selectivity interaction (Lead profiling screen (Eurofins, enzymes, transporters, GPCRs, ion chanels)) EUB0000728a MMP7

ChEMBL ↗

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Target

Matrilysin (CHEMBL4073) ↗

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Primary target Matrilysin

CHEMBL4073

Anchored from Assay target.

Protein identity Matrilysin

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Category	Selectivity assay
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Matrilysin (CHEMBL4073) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Selectivity Literature for EUbOPEN Chemogenomics Library wave 3

EUbOPEN
(2023)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.22	6.22

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4585243	BAY-7598	—	1	6.22

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4585243	BAY-7598	IC50	=	600.0	nM	6.22