Assay Detail
Binding
CHEMBL5215128
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human carboxylesterase using 4-benzoyl-N-butyl-1,8-naphthalimide as substrate by fluorescence based assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.40 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | 5.40 |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | 5.40 |
| CHEMBL5220655 | — | — | 1 | 5.40 |
| CHEMBL498230 | OLEANDEROLIDE | — | 1 | 5.40 |
| CHEMBL5220289 | — | — | 1 | 5.40 |
| CHEMBL455098 | beta-AMYRIN | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL169 | URSOLIC ACID | IC50 | = | 4010.0 | nM | 5.40 |
| CHEMBL168 | OLEANOLIC_ACID | IC50 | = | 4010.0 | nM | 5.40 |
| CHEMBL5220655 | — | IC50 | = | 4010.0 | nM | 5.40 |
| CHEMBL498230 | OLEANDEROLIDE | IC50 | = | 4010.0 | nM | 5.40 |
| CHEMBL5220289 | — | IC50 | = | 4010.0 | nM | 5.40 |
| CHEMBL455098 | beta-AMYRIN | IC50 | = | 4010.0 | nM | 5.40 |