Assay Detail
Toxicity
CHEMBL5215414
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Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 24 hrs by neutral red dye based analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.34 | 4.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5219819 | — | — | 1 | 4.34 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
| CHEMBL5218652 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5219819 | — | IC50 | = | 46100.0 | nM | 4.34 |
| CHEMBL76 | CHLOROQUINE | IC50 | > | 1000000.0 | nM | - |
| CHEMBL5218652 | — | IC50 | = | 127200.0 | nM | - |