Assay Detail
Functional
CHEMBL5215430
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Antiplasmodial activity against multidrug resistant asexual blood stage Plasmodium falciparum Dd2-B2 assessed as inhibition of parasite growth incubated for 72 hrs by SYBR green-based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.72 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5219819 | — | — | 1 | 7.82 |
| CHEMBL4081080 | — | — | 1 | 7.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5219819 | — | IC50 | = | 15.3 | nM | 7.82 |
| CHEMBL4081080 | — | IC50 | = | 24.4 | nM | 7.61 |