Assay Detail
Binding
CHEMBL5215668
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Inhibition of human recombinant integrin alphavbeta6 incubated for 1 hr by ELISA assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.37 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5220367 | — | — | 1 | 5.89 |
| CHEMBL5219297 | — | — | 1 | 5.80 |
| CHEMBL2332369 | — | — | 1 | 4.42 |
| CHEMBL429876 | CILENGITIDE | 3.0 | 1 | - |
| CHEMBL5219601 | — | — | 1 | - |
| CHEMBL5221029 | — | — | 1 | - |
| CHEMBL5220791 | — | — | 1 | - |
| CHEMBL5220898 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5220367 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL5219297 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL2332369 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL429876 | CILENGITIDE | IC50 | - | — | - | |
| CHEMBL5219601 | — | IC50 | > | 5000000.0 | nM | - |
| CHEMBL5221029 | — | IC50 | > | 5000000.0 | nM | - |
| CHEMBL5220791 | — | IC50 | = | 211000.0 | nM | - |
| CHEMBL5220898 | — | IC50 | = | 105000.0 | nM | - |