Assay Detail
Binding
CHEMBL5216202
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mTORC1 in human Jurkat cells assessed as inhibition of S6K phosphorylation incubated for 4 hrs by Western blot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Contemporary mTOR inhibitor scaffolds to diseases breakdown: A patent review (2015-2021).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 10.00 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5218737 | — | — | 1 | 10.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5218737 | — | IC50 | = | 0.1 | nM | 10.00 |