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Assay Detail

CHEMBL5216265

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Binding
Inhibition of IDO1 in human A-172 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type A-172
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Indoleamine 2,3-dioxygenase 1 (CHEMBL4685)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Dual-target inhibitors of indoleamine 2, 3 dioxygenase 1 (Ido1): A promising direction in cancer immunotherapy.
Zhang Y, Hu Z, Zhang J, Ren C, Wang Y.
Eur J Med Chem (2022) 238 : 114524 -114524
PubMed 35696861 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.42 4.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5220107 1 4.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5220107 IC50 = 37700.0 nM 4.42