Assay Detail
Functional
CHEMBL5216355
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Antibacterial activity against Bacillus subtilis NCIM 2079 assessed as reduction in bacterial growth incubated for 8 hrs by absorbance based assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Bacillus subtilis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.68 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5218479 | — | — | 1 | 6.82 |
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | 6.82 |
| CHEMBL1082 | AMOXICILLIN | 4.0 | 1 | 6.82 |
| CHEMBL5219555 | — | — | 1 | 6.68 |
| CHEMBL5220084 | — | — | 1 | 6.68 |
| CHEMBL5219187 | — | — | 1 | 6.60 |
| CHEMBL1727 | CEPHALEXIN ANHYDROUS | 4.0 | 1 | 6.60 |
| CHEMBL5219360 | — | — | 1 | 6.58 |
| CHEMBL5220992 | — | — | 1 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5218479 | — | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL174 | AMPICILLIN | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL1082 | AMOXICILLIN | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5219555 | — | EC50 | = | 210.0 | nM | 6.68 |
| CHEMBL5220084 | — | EC50 | = | 210.0 | nM | 6.68 |
| CHEMBL5219187 | — | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1727 | CEPHALEXIN ANHYDROUS | EC50 | = | 250.0 | nM | 6.60 |
| CHEMBL5219360 | — | EC50 | = | 260.0 | nM | 6.58 |
| CHEMBL5220992 | — | EC50 | = | 280.0 | nM | 6.55 |