Assay Detail
Binding
CHEMBL5216410
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 10 mins by Ellman's method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.59 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4286834 | — | — | 1 | 5.62 |
| CHEMBL4290661 | — | — | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4286834 | — | IC50 | = | 2410.0 | nM | 5.62 |
| CHEMBL4290661 | — | IC50 | = | 2780.0 | nM | 5.56 |