Assay Detail
Binding
CHEMBL5216413
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human MAO-B using kynuramine as substrate preincubated for 10 mins followed by susbstrate addition measured after 20 mins by fluorescent plate reader analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.74 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4286834 | — | — | 1 | 5.74 |
| CHEMBL4290661 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4286834 | — | IC50 | = | 1840.0 | nM | 5.74 |
| CHEMBL4290661 | — | IC50 | > | 100000.0 | nM | - |