Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5216571

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human IM-9 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type IM-9
Confidence 1 — Organism
Curated By Autocuration

Target

IM-9 (CHEMBL614584)
Type CELL-LINE
Organism Homo sapiens

Publication

A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Shahari MSB, Dolzhenko AV.
Eur J Med Chem (2022) 241 : 114645 -114645
PubMed 35981459 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.50 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL193589 1 7.70
CHEMBL36501 1 7.30
CHEMBL5219125 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL193589 IC50 = 20.0 nM 7.70
CHEMBL36501 IC50 = 50.0 nM 7.30
CHEMBL5219125 IC50 < 12.5 nM -