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Assay Detail

CHEMBL5216580

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MHOC-59 cell assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MHOC-59 cell
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Shahari MSB, Dolzhenko AV.
Eur J Med Chem (2022) 241 : 114645 -114645
PubMed 35981459 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.23 7.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5219125 1 7.60
CHEMBL193589 1 7.10
CHEMBL36501 1 6.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5219125 IC50 = 25.0 nM 7.60
CHEMBL193589 IC50 = 80.0 nM 7.10
CHEMBL36501 IC50 = 104.0 nM 6.98