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Assay Detail

CHEMBL5216581

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human AN3-CA cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type AN3-CA
Confidence 1 — Organism
Curated By Autocuration

Target

AN3-CA (CHEMBL1075392)
Type CELL-LINE
Organism Homo sapiens

Publication

A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Shahari MSB, Dolzhenko AV.
Eur J Med Chem (2022) 241 : 114645 -114645
PubMed 35981459 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.47 7.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5219125 1 7.50
CHEMBL193589 1 7.48
CHEMBL36501 1 7.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5219125 IC50 = 32.0 nM 7.50
CHEMBL193589 IC50 = 33.0 nM 7.48
CHEMBL36501 IC50 = 37.0 nM 7.43