Assay Detail
Binding
CHEMBL5216583
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPAAT-beta (unknown origin) expressed in Xenopus laevis oocytes incubated for 3 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Oocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (CHEMBL4772) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.95 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5219455 | — | — | 1 | 8.08 |
| CHEMBL5219496 | — | — | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5219455 | — | IC50 | = | 8.4 | nM | 8.08 |
| CHEMBL5219496 | — | IC50 | = | 15.0 | nM | 7.82 |