Assay Detail
Binding
CHEMBL5216598
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-Raclopride from human 5-HT2AR expressed in HEK293 cells by radioligand binding assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A closer look at N<sup>2</sup>,6-substituted 1,3,5-triazine-2,4-diamines: Advances in synthesis and biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.38 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5219240 | — | — | 1 | 7.41 |
| CHEMBL4873623 | — | — | 1 | 6.68 |
| CHEMBL4520796 | — | — | 1 | 6.37 |
| CHEMBL4860275 | — | — | 1 | 6.32 |
| CHEMBL4086515 | — | — | 1 | 5.75 |
| CHEMBL4447416 | — | — | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5219240 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL4873623 | — | Ki | = | 210.0 | nM | 6.68 |
| CHEMBL4520796 | — | Ki | = | 430.0 | nM | 6.37 |
| CHEMBL4860275 | — | Ki | = | 480.0 | nM | 6.32 |
| CHEMBL4086515 | — | Ki | = | 1760.0 | nM | 5.75 |
| CHEMBL4447416 | — | Ki | = | 1830.0 | nM | 5.74 |