Assay Detail
Functional
CHEMBL5216753
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Antiproliferative activity against mouse B16 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Comparative analysis of p-terphenylquinone and seriniquinone derivatives as reactive oxygen species-modulating agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.86 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4437459 | — | — | 1 | 6.75 |
| CHEMBL4438542 | — | — | 1 | 5.62 |
| CHEMBL5218704 | — | — | 1 | 5.55 |
| CHEMBL5219417 | — | — | 1 | 5.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4437459 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL4438542 | — | IC50 | = | 2380.0 | nM | 5.62 |
| CHEMBL5218704 | — | IC50 | = | 2830.0 | nM | 5.55 |
| CHEMBL5219417 | — | IC50 | = | 2950.0 | nM | 5.53 |