Assay Detail
Binding
CHEMBL5216879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HJ-DNA dependent Pseudomonas aeruginosa RuvB ATPase activity expressed in Escherichia coli BL21(DE3) assessed as inhibition of ATP hydrolysis preincubated with compound followed by ATP addition and measured after 1 hr by Kinase-Glo reagent based luminescence analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of small-molecule inhibitors of the DNA repair proteins RuvAB from Pseudomonas aeruginosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.63 | 5.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL449392 | CORILAGIN | — | 1 | 5.63 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL449392 | CORILAGIN | IC50 | = | 2320.0 | nM | 5.63 |