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Assay Detail

CHEMBL5216883

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Binding
Binding affinity to CM5 chip immobilized Pseudomonas aeruginosa wild type RuvB expressed in Escherichia coli BL21(DE3) assessed as dissociation constant measured for 180 sec by surface plasmon resonance analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Identification of small-molecule inhibitors of the DNA repair proteins RuvAB from Pseudomonas aeruginosa.
Dai L, Lu L, Zhang X, Wu J, Li J, Lin Z.
Bioorg Med Chem (2022) 73 : 117022 -117022
PubMed 36155320 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL449392 CORILAGIN 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL449392 CORILAGIN Kd = 130.0 nM 6.89