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Assay Detail

CHEMBL5217356

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK9 (unknown origin) using [33-p]-ATP as substrate incubated for 40 mins by Western blot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 9 (CHEMBL3116)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Natural Product-Inspired Targeted Protein Degraders: Advances and Perspectives.
Li J, Cai Z, Li XW, Zhuang C.
J Med Chem (2022) 65 : 13533 -13560
PubMed 36205223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.72 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL16171 WOGONIN 1 6.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL16171 WOGONIN IC50 = 190.0 nM 6.72