Assay Detail
Functional
CHEMBL5217397
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human IN1760 cells assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | IN1760 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent Scaffold Hopping Applications in Central Nervous System Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.44 | 4.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL203360 | — | — | 1 | 4.44 |
| CHEMBL2349386 | 2-(2'-HYDROXYPHENYL)-1H-INDOLE | — | 1 | - |
| CHEMBL1650631 | — | — | 1 | - |
| CHEMBL4455327 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL203360 | — | EC50 | = | 36000.0 | nM | 4.44 |
| CHEMBL2349386 | 2-(2'-HYDROXYPHENYL)-1H-INDOLE | EC50 | = | 185000.0 | nM | - |
| CHEMBL1650631 | — | EC50 | > | 2500000.0 | nM | - |
| CHEMBL4455327 | — | EC50 | > | 1000000.0 | nM | - |