Assay Detail
Functional
CHEMBL5223543
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Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances on synthesis and biological activities of aurones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.24 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL326574 | — | — | 1 | 5.38 |
| CHEMBL326079 | — | — | 1 | 5.38 |
| CHEMBL324265 | — | — | 1 | 5.37 |
| CHEMBL113771 | — | — | 1 | 5.23 |
| CHEMBL115120 | — | — | 1 | 5.05 |
| CHEMBL116391 | — | — | 1 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL326574 | — | IC50 | = | 4120.0 | nM | 5.38 |
| CHEMBL326079 | — | IC50 | = | 4120.0 | nM | 5.38 |
| CHEMBL324265 | — | IC50 | = | 4320.0 | nM | 5.37 |
| CHEMBL113771 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL115120 | — | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL116391 | — | IC50 | = | 9120.0 | nM | 5.04 |