Assay Detail
Functional
CHEMBL5223582
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Cytotoxicity against human OCI-AML2 cells assessed as cell growth inhibition measured after 72 hrs by spectrophotometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OCI-AML2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Proteases and Their Modulators in Cancer Therapy: Challenges and Opportunities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.37 | 7.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5287669 | — | — | 1 | 7.12 |
| CHEMBL4297310 | DORDAVIPRONE | 3.0 | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5287669 | — | IC50 | = | 76.0 | nM | 7.12 |
| CHEMBL4297310 | DORDAVIPRONE | IC50 | = | 2400.0 | nM | 5.62 |