Assay Detail
Binding
CHEMBL5223590
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Inhibition of MMP-2 (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Proteases and Their Modulators in Cancer Therapy: Challenges and Opportunities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.13 | 9.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5268799 | — | — | 1 | 9.17 |
| CHEMBL5267731 | — | — | 1 | 8.43 |
| CHEMBL34206 | — | — | 1 | 8.40 |
| CHEMBL5281153 | — | — | 1 | 8.32 |
| CHEMBL370685 | — | — | 1 | 7.58 |
| CHEMBL483857 | — | — | 1 | 7.55 |
| CHEMBL3585766 | — | — | 1 | 7.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5268799 | — | IC50 | = | 0.67 | nM | 9.17 |
| CHEMBL5267731 | — | IC50 | = | 3.7 | nM | 8.43 |
| CHEMBL34206 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL5281153 | — | IC50 | = | 4.8 | nM | 8.32 |
| CHEMBL370685 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL483857 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL3585766 | — | IC50 | = | 32.8 | nM | 7.48 |