Assay Detail
Binding
CHEMBL5223602
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Inhibition of human BCL6 BTP domain measured by cell reporter assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.02 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4100303 | — | — | 1 | 7.06 |
| CHEMBL4092565 | — | — | 1 | 7.00 |
| CHEMBL4064865 | — | — | 1 | 6.70 |
| CHEMBL4094351 | — | — | 1 | 5.70 |
| CHEMBL5273385 | — | — | 1 | 5.51 |
| CHEMBL5277976 | — | — | 1 | 5.13 |
| CHEMBL5207356 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4100303 | — | IC50 | = | 87.0 | nM | 7.06 |
| CHEMBL4092565 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4064865 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL4094351 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL5273385 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL5277976 | — | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL5207356 | — | IC50 | = | 8800.0 | nM | 5.06 |