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Assay Detail

CHEMBL5223603

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CK2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Casein kinase 2 (CHEMBL3832943)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond.
Ai Y, Hwang L, MacKerell AD, Melnick A, Xue F.
J Med Chem (2021) 64 : 4333 -4358
PubMed 33844535 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 6.19 6.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4094351 1 6.19
CHEMBL4100303 1 -
CHEMBL4092565 1 -
CHEMBL4064865 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4094351 IC50 = 640.0 nM 6.19
CHEMBL4100303 IC50 > 10000.0 nM -
CHEMBL4092565 IC50 > 10000.0 nM -
CHEMBL4064865 IC50 > 10000.0 nM -