Assay Detail
Binding
CHEMBL5223605
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Binding affinity to human BCL6 BTP domain assessed as dissociation constant by biolayer interferometry assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.82 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4538610 | — | — | 1 | 6.43 |
| CHEMBL4077392 | — | — | 1 | 5.92 |
| CHEMBL4061302 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4538610 | — | Kd | = | 370.0 | nM | 6.43 |
| CHEMBL4077392 | — | Kd | = | 1200.0 | nM | 5.92 |
| CHEMBL4061302 | — | Kd | = | 7900.0 | nM | 5.10 |