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Assay Detail

CHEMBL5223680

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [1251]AB-MEC from human A3 receptor assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Adenosine receptor A3 (CHEMBL256)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The Medicinal Chemistry of Caffeine.
Faudone G, Arifi S, Merk D.
J Med Chem (2021) 64 : 7156 -7178
PubMed 34019396 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.64 6.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL138746 1 6.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL138746 Ki = 229.0 nM 6.64