Assay Detail
Binding
CHEMBL5223681
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]IABOPX to human A2B receptor assessed as inhibition constant by fluorescence based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Medicinal Chemistry of Caffeine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.28 | 8.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17002 | — | — | 1 | 8.86 |
| CHEMBL273807 | — | — | 1 | 8.71 |
| CHEMBL8565 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17002 | — | Ki | = | 1.39 | nM | 8.86 |
| CHEMBL273807 | — | Ki | = | 1.97 | nM | 8.71 |
| CHEMBL8565 | — | Ki | = | 53.4 | nM | 7.27 |