Assay Detail
Binding
CHEMBL5223817
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant farnesyltransferase using [3H]geranylgeranyldiphosphate and Ha-Ras-CVLL as substrate assessed as inhibition of farnesylation by immunoblot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.72 | 8.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298734 | LONAFARNIB | 4.0 | 1 | 8.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298734 | LONAFARNIB | IC50 | = | 1.9 | nM | 8.72 |