Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5223829

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant ROCK2 by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Rho-associated protein kinase 2 (CHEMBL2973)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.
Gendaszewska-Darmach E, Garstka MA, Błażewska KM.
J Med Chem (2021) 64 : 9677 -9710
PubMed 34236862 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.28 7.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2023158 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2023158 IC50 = 52.0 nM 7.28