Assay Detail
Binding
CHEMBL5223834
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Rac1 GTPase in human breast cancer cell line treated for 24 hrs by western blot assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Breast cancer cell line |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Ras-related C3 botulinum toxin substrate 1 (CHEMBL6094) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting Small GTPases and Their Prenylation in Diabetes Mellitus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5290216 | MBQ-167 | 1.0 | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5290216 | MBQ-167 | IC50 | = | 100.0 | nM | 7.00 |