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Assay Detail

CHEMBL5223975

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Binding
Inhibition of human MDM4 by SRP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Protein Mdm4 (CHEMBL1255126)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions.
Zhang S, Lou J, Li Y, Zhou F, Yan Z, Lyu X, Zhao Y.
J Med Chem (2021) 64 : 10621 -10640
PubMed 34286973 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.68 9.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3657129 1 9.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3657129 IC50 = 0.21 nM 9.68