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Assay Detail

CHEMBL5224206

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of soybean LOX15 using arachidonic acid preincubated for 5 mins followed by substrate addition and measured after 5 mins by microplate spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Glycine max
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Recent advancements in chromone as a privileged scaffold towards the development of small molecules for neurodegenerative therapeutics.
Madhav H, Jameel E, Rehan M, Hoda N.
RSC Med Chem (2022) 13 : 258 -279
PubMed 35434628 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.91 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5270908 1 5.00
CHEMBL5270046 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5270908 IC50 = 10000.0 nM 5.00
CHEMBL5270046 IC50 = 15000.0 nM 4.82