Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5224403

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 24 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562
Confidence 1 — Organism
Curated By Autocuration

Target

K562 (CHEMBL385)
Type CELL-LINE
Organism Homo sapiens

Publication

Evolution of 3-(4-hydroxyphenyl)indoline-2-one as a scaffold for potent and selective anticancer activity.
Boudreau MW, Hergenrother PJ.
RSC Med Chem (2022) 13 : 711 -725
PubMed 35814932 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.91 4.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5266426 1 4.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5266426 IC50 = 12400.0 nM 4.91