Assay Detail

CHEMBL5224432

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of CDK19/Cyclin C (unknown origin) by LanthaScreen binding assay

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Cyclin-C/Cyclin-dependent kinase 19 (CHEMBL3883323) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Cyclin-C/Cyclin-dependent kinase 19 (CHEMBL3883323) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Cyclin-C/Cyclin-dependent kinase 19

CHEMBL3883323

Anchored from Assay target.

Protein identity Cyclin-C/Cyclin-dependent kinase 19

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	7 — Homologous single protein target
Curated By	Autocuration

Target

Cyclin-C/Cyclin-dependent kinase 19 (CHEMBL3883323) ↗

Type	PROTEIN COMPLEX
Organism	Homo sapiens

Publication

CDK9 inhibitors in cancer research.

Huang Z, Wang T, Wang C, Fan Y.
RSC Med Chem (2022) 13 : 688 -710
PubMed 35814933 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.57	8.57

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL359963	GW805758X	—	1	8.57

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL359963	GW805758X	IC50	=	2.7	nM	8.57