Assay Detail
Binding
CHEMBL5224455
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK2 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
CDK9 inhibitors in cancer research.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.57 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5199065 | ISTISOCICLIB | 2.0 | 1 | 6.40 |
| CHEMBL5285499 | — | — | 1 | 4.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5199065 | ISTISOCICLIB | IC50 | = | 396.0 | nM | 6.40 |
| CHEMBL5285499 | — | IC50 | = | 18200.0 | nM | 4.74 |