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Assay Detail

CHEMBL5225008

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mouse Nav1.7 at -70 mV holding potential by manual patch-clamp assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sodium channel protein type 9 subunit alpha (CHEMBL3414411)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Inhibition of Na<sub>V</sub>1.7: the possibility of ideal analgesics.
Kitano Y, Shinozuka T.
RSC Med Chem (2022) 13 : 895 -920
PubMed 36092147 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.41 8.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4061793 1 8.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4061793 IC50 = 3.9 nM 8.41