Assay Detail
Binding
CHEMBL5225014
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse Nav1.7 at voltage yielding 20 to 50% channel inactivation by automated patch-clamp assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium channel protein type 9 subunit alpha (CHEMBL3414411) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Inhibition of Na<sub>V</sub>1.7: the possibility of ideal analgesics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.73 | 7.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3945969 | — | — | 1 | 7.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3945969 | — | IC50 | = | 18.6 | nM | 7.73 |