Assay Detail
Functional
CHEMBL5225023
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vivo inhibition of Nav1.7 in IEM mouse model of aconitine-induced pain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium channel protein type 9 subunit alpha (CHEMBL3414411) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Inhibition of Na<sub>V</sub>1.7: the possibility of ideal analgesics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.58 | 6.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4444707 | — | — | 1 | 6.01 |
| CHEMBL4471012 | — | — | 1 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4444707 | — | IC50 | = | 970.0 | nM | 6.01 |
| CHEMBL4471012 | — | IC50 | = | 7300.0 | nM | 5.14 |