Assay Detail
Functional
CHEMBL5225159
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Anti-proliferative against human SK-MEL-28 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-MEL-28 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-activity relationships of mixed σ<sub>1</sub>R/σ<sub>2</sub>R ligands with antiproliferative and anticancer effects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.29 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5283424 | — | — | 1 | 4.30 |
| CHEMBL4650909 | — | — | 1 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5283424 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL4650909 | — | IC50 | = | 52000.0 | nM | 4.28 |