Assay Detail
Binding
CHEMBL5225353
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of TG2 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Protein-glutamine gamma-glutamyltransferase (CHEMBL2730) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The Emerging Landscape of Small-Molecule Therapeutics for the Treatment of Huntington's Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.39 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2086528 | — | — | 1 | 8.00 |
| CHEMBL5283861 | — | — | 1 | 7.21 |
| CHEMBL2152204 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2086528 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5283861 | — | IC50 | = | 62.0 | nM | 7.21 |
| CHEMBL2152204 | — | IC50 | = | 110.0 | nM | 6.96 |