Assay Detail
Binding
CHEMBL5225392
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse PI3Kdelta expressed in insect cells assessed as fluorescence polarization incubated for 30 mins by ATP competitive assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (CHEMBL2216745) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.80 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1234354 | PF-04691502 | 2.0 | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1234354 | PF-04691502 | IC50 | = | 1.6 | nM | 8.80 |